I-Technology Innovation: I-Synthesis ye-Cosmetic-Grade Phenoxyethanol esuka kwi-Ethylene Oxide kunye ne-Phenol

Intshayelelo

I-Phenoxyethanol, i-preservative esetyenziswa ngokubanzi kwi-cosmetics, ifumene ukugqwesa ngenxa yokusebenza kwayo ngokuchasene nokukhula kwe-microbial kunye nokuhambelana nokuqulunqwa kwesikhumba. Ngokwemveli idityaniswe nge-Williamson ether synthesis isebenzisa i-sodium hydroxide njenge-catalyst, inkqubo ihlala ijongana nemiceli mngeni efana nokuqulunqwa kwemveliso, ukungasebenzi kakuhle kwamandla, kunye neenkxalabo zokusingqongileyo. Ukuqhubela phambili kwamva nje kwi-catalytic chemistry kunye nobunjineli obuluhlaza kuvule indlela entsha: ukusabela ngokuthe ngqo kwe-ethylene oxide kunye nephenol ukuvelisa ubunyulu obuphezulu, i-cosmetic-grade phenoxyethanol. Olu tshintsho luthembisa ukucacisa ngokutsha imigangatho yemveliso yemizi-mveliso ngokwandisa uzinzo, ukulinganisa, kunye nokusebenza kakuhle kweendleko.

Imingeni kwiiNdlela eziqhelekileyo

I-classical synthesis ye-phenoxyethanol ibandakanya ukuphendula kwe-phenol kunye ne-2-chloroethanol kwiimeko ze-alkaline. Ngelixa isebenzayo, le ndlela ivelisa i-sodium chloride njenge-byproduct, efuna amanyathelo abanzi okucoca. Ukongeza, ukusetyenziswa kweziphakathi ezineklorini kuphakamisa iinkxalabo zokusingqongileyo kunye nokhuseleko, ngakumbi ngokuhambelana nokutshintsha kweshishini lezithambiso ukuya kwimithetho-siseko “yekhemistri eluhlaza”. Ngaphezu koko, ulawulo lokuphendula olungaguqukiyo luhlala lukhokelela kukungcola okunje nge-polyethylene glycol derivatives, ebeka esichengeni umgangatho wemveliso kunye nokuthotyelwa komgaqo.

Utshintsho lweTekhnoloji

Impumelelo ilele kumanyathelo amabini enkqubo yokukhuthaza ephelisa i-reagents eneklorini kunye nokunciphisa inkunkuma:

Ukusebenza kweEpoxide:I-ethylene oxide, i-epoxide esebenzayo kakhulu, ivula i-ring-ring phambi kwe-phenol. I-novel heterogeneous acid catalyst (umzekelo, i-sulfonic acid exhaswa yi-zeolite) iququzelela eli nyathelo phantsi kobushushu obuphakathi (60-80 ° C), ukuphepha iimeko zokusebenzisa amandla.

I-Etherification eKhethekileyo:I-catalyst ikhokelela ekuphenduleni kwi-phenoxyethanol ngelixa icinezela ukuphendula kwe-polymerization. Iinkqubo zokulawula iinkqubo eziphakamileyo, kubandakanywa iteknoloji ye-microreactor, iqinisekisa ukushisa okuchanekileyo kunye nokulawulwa kwe-stoichiometric, ukufezekisa> 95% amazinga okuguqulwa.

Izinto eziluncedo ezingundoqo zeNdlela eNtsha

Uzinzo:Ngokutshintshela i-chlorinated precursors kunye ne-ethylene oxide, inkqubo iphelisa imilambo yenkunkuma eyingozi. Ukusetyenziswa kwakhona kwe-catalyst kunciphisa ukusetyenziswa kwezinto eziphathekayo, ukulungelelanisa neenjongo zoqoqosho ezijikelezayo.

Ubunyulu noKhuseleko:Ukungabikho kwe-chloride ion kuqinisekisa ukuthotyelwa kwemimiselo engqongqo ye-cosmetic (umzekelo, i-EU Cosmetics Regulation No. 1223/2009). Iimveliso zokugqibela zidibana> 99.5% ubunyulu, obubaluleke kakhulu kwizicelo zokhathalelo lwesikhumba.

Ubuchule boQoqosho:Amanyathelo okucoca alula kunye neemfuno ezisezantsi zamandla zinciphisa iindleko zemveliso nge ~ 30%, zibonelela ngeenzuzo ezikhuphisanayo kubavelisi.

Iimpembelelo zoShishino

Olu tshintsho lufika ngexesha elibalulekileyo. Ngemfuno yehlabathi ye-phenoxyethanol ekuqikelelwa ukuba iza kukhula nge-5.2% CAGR (2023-2030), iqhutywa ziindlela zokuthambisa zendalo kunye nendalo, abavelisi bajongana noxinzelelo lokwamkela iindlela zokusebenzisa i-eco-friendly. Iinkampani ezifana ne-BASF kunye ne-Clariant sele ziphonononge iinkqubo ezifanayo ze-catalytic, ukunika ingxelo yokunciphisa i-carbon footprints kunye nexesha elikhawulezayo lokuya kwimarike. Ngaphaya koko, indlela yokwandiswa komgangatho ixhasa imveliso enabekelwe amagunya, ivumela amakhonkco obonelelo ngengingqi kunye nokunciphisa izinto ezikhutshwayo ezinxulumene nolungiselelo.

Amathemba ekamva

Uphando oluqhubekayo lujolise kwi-bio-based ethylene oxide evela kwimithombo evuselelekayo (umzekelo, i-ethanol yommoba) ukuqhubela phambili inkqubo yokukhupha ikhabhoni. Ukudityaniswa neeplatifti zokuphucula ukusabela okuqhutywa yi-AI kunokonyusa ukuqikelelwa kwesivuno kunye nobomi obuluncedo. Loo nkqubela phambili ibeka i-phenoxyethanol synthesis njengomzekelo wokwenziwa kweekhemikhali ezizinzileyo kwicandelo lezithambiso.

Ukuqukumbela

I-catalytic synthesis ye-phenoxyethanol esuka kwi-ethylene oxide kunye ne-phenol ibonisa indlela ubugcisa obutsha obunokulungelelanisa ngayo ukusebenza kakuhle kwezoshishino kunye nokunyamekela kokusingqongileyo. Ngokujongana nemida yeendlela zelifa, le ndlela ayifezekisi kuphela iimfuno eziguqukayo zentengiso yezithambiso kodwa ikwamisela umyinge wekhemikhali eluhlaza kwimveliso yeekhemikhali ezikhethekileyo. Njengoko izinto ezikhethwa ngabathengi kunye nemigaqo iqhubeka nokubeka phambili uzinzo, ezo mpumelelo ziya kuhlala ziyimfuneko kwinkqubela phambili yoshishino.

Eli nqaku ligxininisa ukuhlangana kwekhemistri, ubunjineli, kunye nokuzinza, ukubonelela ngethemplate yezinto ezintsha ezizayo kwi-cosmetic ingredient.